WHAT IF YOU COULD CHOOSE YOUR AGE?
LANCÔME SETS A NEW STANDARD FOR LONGEVITY ADVANCEMENTS,
FORMULATED WITH DOCTOR RECOMMENDED UROLITHIN-A LONGEVITY SUPPLEMENT, NOW IN ADVANCED SKINCARE1
INTRODUCING
NEW ABSOLUE LONGEVITY MD
META DISCOVERY
Longevity translates into living longer while maintaining energy, vitality, strength, and resilience as we age. Staying healthy, feeling our best, and reaching our full potential lifespan under ideal conditions. Thanks to advances in science and technology, longevity is no longer a distant ideal but a reality, supported by smarter habits, care practices, and innovations that don’t just add years, but also help preserve quality of life. As lifespans lengthen, the focus shifts from aging as a decline to aging as something that can be supported, optimized, and lived to the fullest.
Just as longevity science seeks to extend years of cellular vitality, longevity in the field of beauty must extend years of resilience, structural integrity and life-force far beyond what was once thought possible. It fully aligns with what women want today – to live better, not just longer.
Within the longevity landscape, skin’s appearance is no longer aesthetic – it is a critical biological indicator. As the body’s largest and most visible organ, the skin acts as a living mirror of our individual healthspan, the period of life spent in optimal vitality. While chronological age remains fixed, biological age represents a dynamic reality that can be measured and influenced. In this new paradigm, chronological age is merely a number, the true priority is skin’s visible biological age, the only age you can reverse. By decoding the skin’s biological mechanisms, skincare becomes a powerful pillar in the field of longevity science, offering a unique opportunity to optimize individual skin’s visible aging trajectories for a future of enduring vitality.
LANCÔME AT THE FOREFRONT OF LONGEVITY SCIENCE
Lancôme’s commitment to pioneering longevity represents a fundamental shift in how beauty approaches aging, moving beyond the pursuit of looking younger toward fostering well-being, vitality, and confidence throughout our individual journeys. As global leader in the beauty industry, Lancôme is not following the longevity movement but actively shaping it.
Lancôme’s relentless drive for innovation introduces the ultimate platform of open-innovation with cutting-edge longevity partnerships. By cultivating an ongoing collaborative strategy with the most advanced players in the field—exemplified by its breakthrough partnerships with Swiss longevity biotech Timelineâ and Korean beauty tech startup NanoEntekTM—Lancôme acts as a progressive bridge between biotech and high-performance longevity consumer solutions. These strategic alliances with renowned partners allow Lancôme to translate complex scientific discoveries into a new era of beauty, effectively setting the standards for the beauty industry’s future.
Ultimately, Lancôme presents a more integrative and proactive vision that reimagines the pathways of aging through science, education, personalized analysis and long-term innovation. This leadership carries responsibility: to empower consumers with knowledge, to set new standards for the category, and to promote an inclusive, optimistic vision of ageing.
For Lancôme, longevity is not a moment in time, but an ongoing commitment. It is the future of beauty itself.
LANCÔME ADVANCES A RADICAL, PROACTIVE, SCIENCE-DRIVEN VISION OF AGING
As a global progress powerhouse, Lancôme draws on the L’Oréal group’s decades of research and unprecedented investment in longevity science. The brand combines unique scientific heritage spanning over 90 years, with breakthrough skincare solutions continuously disrupting the beauty industry.
Powered by the L’Oréal Group’s advanced biological expertise and breakthrough technologies, Lancôme is pioneering Longevity Integrative Science™—a proactive approach that decodes aging mechanisms at the molecular, cellular, and tissue levels to support the skin’s natural renewal, resilience, and healthy-looking appearance over time.
LONGEVITY AI CLOUD: MAPPING BIOMARKERS ONTO THEIR IMPACTS
At the core of Longevity Integrative Science™ lies the Longevity AI Cloud—a map of 267 biomarkers revealing nine biological hallmarks at the heart of skin aging. Visualized through the Longevity Wheel, these hallmarks guide Lancôme’s approach to advanced longevity skincare.
THE LONGEVITY WHEEL: A FRAMEWORK FOR LONGEVITY SKINCARE
Backed by more than 20 years of longevity research and developed by leading L’Oréal group researchers, the Longevity Wheel, to Lancôme, is built on nine biological hallmarks. These nine hallmarks are organized into three functional clusters, reflecting distinct stages in the skin aging trajectory:
⦁ Structural functions represent the earliest phase, when damage to DNA and proteins begins to alter the cell’s internal architecture—often before visible signs appear.
⦁ Metabolic functions are impacted next: as cells lose functional capacity, damage accumulates and early signs of aging begin to appear.
⦁ Signaling functions mark the later stage, when damaged cells send incorrect signals, disrupting tissue function, leading to visible aging cues such as deep wrinkles.
By mapping these mechanisms into a single, coherent system, the Longevity Wheel enables the development of three targeted intervention models, each designed to act at a specific stage of skin aging.
Inspired by Longevity Integrative Science™, Absolue Longevity MD translates skin longevity science into targeted intervention models. Out of cooperation with longevity medical specialists, Absolue Longevity MD proactively targets visible and invisible signs of aging to preserve strength, vitality, and radiance over time.
NEW ABSOLUE LONGEVITY MD
Meta Discovery
Formulated with Mitopure™ by Timeline, doctor recommended urolithin-A longevity supplement, now in advanced skincare1.
Lancôme introduces Absolue Longevity MD, our first meta discovery skincare range grounded in Longevity Integrative Science™ to proactively reverse on the skin’s visible biological age at every life stage.
Comprised of three precisely calibrated intervention models, this comprehensive solution addresses deep and imperceptible skin damages to preserve strength, vitality, and radiance.
MITOPURE™ BY TIMELINE: LONGEVITY BIOTECH MEETS ADVANCED SKINCARE
Lancôme introduces Mitopure™ by Timeline.
Throughout the skin’s aging trajectory, one biological function plays a critical role in longevity: mitochondrial health. Mitochondria are the engines of skin cells, driving 80% energy production, renewal, and resilience. As skin ages, mitochondrial efficiency declines, contributing to visible signs of aging and loss of vitality. Supporting this function is essential to preserving skin performance over time.
In its search for revolutionary longevity actives, L’Oréal invested in Timeline, a Swiss biotech company dedicated to advancing healthy human function through longevity science. Timeline was recently recognized in the prestigious XPRIZE Healthspan competition, selected from hundreds of teams for its innovative, safe, and science-backed approach.
Mitopure™ is the proprietary molecule that powers Timeline’s doctor-recommended longevity supplement. It is a 98.5% pure and micronized form of Urolithin-A, proven to stimulate the mitochondrial recycling process and recognized as a potent cellular battery rejuvenator.
This unprecedented technology is backed by more than $50 Million in R&D investment and 15 years of research by leading scientists, rigorous clinical studies, and an extensive intellectual property portfolio. Lancôme’s new longevity skincare launch marks Mitopure™’s first deployment at global scale through a major beauty brand, shifting longevity-focused skincare from a niche proposition into broader consumer access.
Through this partnership, Lancôme leverages Timeline’s pioneering expertise in Urolithin A and translates it into high-performance topical formulas, meeting the highest standards of efficacy and purity.
The result is a longevity protocol that goes beyond correcting skin as it ages, to supporting its visible biological properties at its root, and helping to guide its visible aging trajectory over time.
TARGETING BIOLOGICAL SHIFTS WITH THREE INTERVENTION MODELS
INFUSING BREAKTHROUGH LONGEVITY ACTIVE MITOPURE™
WITH LANCÔME’S PROPRIETARY COMPOUNDS
As skin needs evolve over time—strong prevention early on, then progressively more correction as the years pass—Lancôme has designed three intervention models ANTICIPATE, INTERCEPT, RESET to address each stage of the skin’s aging trajectory.
Building on its knowledge of its mitochondrial support function capability, Lancôme goes further by creating proprietary compounds that modulate the balance between preventive and corrective action differently for every intervention model.
Precisely calibrated to the biological shifts that occur as skin changes, each compound is a tailored blend of active ingredients aligned with the skin’s visible biological age and its rate of visible aging—ensuring the right solution is delivered at the right moment.
EARLY ONSET
ANTICIPATE
SKIN’S CHRONOLOGICAL AGE: UNDER 35 YEARS
For younger skin, proactively preserving its youthful potential.
Acting on aging signs before they appear.
In the early stages, lifestyle shifts can silently disrupt skin health, diminishing its youthful look capital.
A singular cream is designed to protect skin’s youthful potential, strengthening resilience, revitalizing cells, and laying the foundation for long-lasting vitality. At this stage, the priority is to reinforce skin before visible change appears.
THE ANTICIPATE COMPOUND
Within the ANTICIPATE intervention model, the primary objective is to have a proactive approach that helps protect the skin from everyday stressors to support a more youthful-looking appearance over time.
ANTICIPATE compound: Protective flavonoids, skin-recognizable sugars, and amino-acid derivatives, designed to support skin resilience—helping address early signs of aging as they emerge, before they become visible.
“Targets signs of aging before they appear, by preserving skin’s youth capital before it starts to deplete.”
– Dr. Annie Black, Lancôme International Scientific Director.
ANTICIPATE CREAM RESULTS
-16% incoming fine lines2
-50% incoming skin oxidation3
MID-AGE
INTERCEPT
SKIN’S CHRONOLOGICAL AGE: BETWEEN 35 & 55 YEARS
For skin in its mid-life phase, when cellular aging accelerates.
Tackling aging signs as they appear.
In midlife, less skin cell renewal begins to undermine the skin’s integrity, driving premature aging. A powerful serum and cream are designed to counter visible signs of aging dysfunction, boosting skin renewal, restoring density, and enhancing glow. At this stage, skin benefits from targeted correction and daily support to keep renewal at its best.
THE INTERCEPT COMPOUND
Within the INTERCEPT intervention model, the primary objective is to help support the skin’s natural renewal capacity over time.
INTERCEPT compound: Complex of amino-acid building blocks, an NAD+ precursor, skin-recognizable sugars, and amino-acid derivatives, designed to support skin renewal—helping intercept visible signs of aging as they appear
“Recharges skin’s youth to regain peak performance, when aging accelerates and cellular dysfunction becomes visible.”
– Dr. Annie Black, Lancôme International Scientific Director.
INTERCEPT SERUM & CREAM RESULTS:
+76% tightened skin4
+84M new surface cells5
MATURE AGE
RESET
SKIN’S CHRONOLOGICAL AGE: OVER 55 YEARS
For more mature skin, when visible signs are most established.
Addressing aging signs after they appear.
Mature skin is subject to senescent cells—”zombie cells” that have stopped dividing but have not yet died—which can accumulate in the body and harm healthy skin.
A dedicated serum and cream are designed to restore vitality— to help supporting skin recovery, revitalizing cells and rebuilding structure while rebalancing function. At this stage, the goal is to help skin perform as if time had unfolded differently.
THE RESET COMPOUND
Within the RESET intervention model, the primary objective is a proactive approach that helps support skin recovery over time.
RESET compound: Signaling, biomimetic, and skin-recognizable sugars, an NAD+ precursor, and amino-acid derivatives, designed to support skin recovery—helping reset visible signs of aging after they appear.
“Reverse skin visible damages to restore vitality and reignite skin at its best.”
– Dr. Annie Black, Lancôme International Scientific Director.
RESET SERUM & CREAM RESULTS:
+55% bouncy skin6
+15% faster surface cell renewal7
Each phase features a dedicated cream plus an accompanying serum for Intercept and Reset. Formulated with Lancôme’s biggest innovative active breakthrough since Pro-Xylane, 20 years ago, Mitopure™ by Timeline, the regimen is informed by over a decade of integrative scientific research.
Each routine is designed to be used exclusively—products are not interchangeable or layered across stages. The ritual’s precision lies in its intentionality: one routine at one time, for maximum biological relevance and visible impact.
The result is a protocol that doesn’t just treat skin as it ages. It places control of the skin’s visible biological age into the hands of the user.
A LEGACY REIMAGINED FOR MODERNITY AND SUSTAINABILITY
Inspired by the iconic 1965 Absolue packaging, the design of Absolue Longevity MD revisits a moment of bold innovation in Lancôme’s history, reinterpreted through a contemporary lens. Rooted in a heritage of excellence and innovation, the packaging draws from Lancôme’s beauty archives, expressing the timeless Absolue codes with modern precision. This rebirth honors the past while looking forward elevated, refined, and intentionally designed to last. Refillable by design, the Absolue Longevity MD Intercept Cream reflects Lancôme’s commitment to longevity not only in skin, but in creation itself.
Comparing the weight of each material used in one jar versus one refill of the Absolue Longevity MD Intercept cream you help save:
100% glass12
40% plastic12
31% cardboard12
95% metal12
LANCÔME UNLOCKS SKIN’S VISIBLE BIOLOGICAL AGE
Charting individual skin aging journeys with radical beauty tech
Science decodes the skin. Absolue Longevity MD rewrites its future.
Launching alongside the range, Cell BioPrint™ marks a new generation of Lancôme Beauty Tech, developed with our Korean partner NanoEnTek to analyze five skin-surface biomarkers, help interpret the skin’s visible biological age, and suggest personalized longevity skincare protocols.
INTRODUCING CELL BIOPRINT™
Cell BioPrint™ is a first-of-its-kind longevity skin analysis device that brings advanced lab-grade testing into a sleek, credit-card–sized format. Using protein science (proteomics) and “lab-on-a-chip” technology, it analyzes key biomarkers to help reveal your skin’s visible biological age, how fast it’s aging, and its future needs profile—so you understand what your skin needs today and what it may need next. Cell BioPrint™ establishes a precise snapshot of the skin’s surface present state while modeling its aging trajectory at a molecular level. It identifies vulnerabilities, resilience factors, and early markers, enabling a shift from reactive correction to proactive care. By anticipating concerns such as the likelihood of pigmentation or other visible signs before they appear, it allows preventive interventions tailored to each individual.
Based on this analysis, Cell BioPrint™ prescribes a personalized longevity care path aligned with the skin’s visible biological needs. The protocol may prioritize ANTICIPATE to help preserve skin and delay first signs, INTERCEPT to treat early signs and slow their progression, or RESET to address established signs — sometimes blending approaches — so the routine matches exactly what the skin needs now, and how it will evolve over time.
This fusion of biology and technology marks a turning point for skincare. For the first time, visible age can be measured, transforming personalization from a trend into a scientific reality. More than a diagnostic tool, Cell BioPrint™ is an instrument of precision beauty — delivering predictive, data-driven, and adaptive skincare designed to empower individuals to optimize their skin’s longevity at every stage of life.
1 Based on IQVIA study, December 2025, 21 US doctors self-reported as longevity doctors.
2Clinical scoring, 76 persons after 3 months.
3Ex vivo test on skin surface oxidation with Anticipate Cream Formula.
4Instrumental test, 40 persons.
5Instrumental test, 31 persons, 22days.
6instrumental test, 40 persons.
7Instrumental test, 32 persons, 22days.
8 Comparing the weight of each, material used in one jar versus one refill
